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JWH-020: Naphthoylindole: 128 ± 17: 205 ± 20: CB 1 (1.6x) JWH-030: Naphthoylpyrrole: 87 ± 3: 320 ± 127: CB 1 (3.7x) JWH-031: Naphthoylpyrrole: 399 ± 109: JWH-032: Naphthoylpyrrole >10000 >10000 — JWH-033: Naphthoylpyrrole: 666 ± 77: JWH-036: Naphthoylpyrrole: 309 ± 11: JWH-042 [6] Naphthoylindole >10000: 5050 ± 192: CB 2: JWH-043 [6 ...
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
JWH-398; JWH-424; This page was last edited on 20 February 2023, at 10:25 (UTC). Text is available under the Creative Commons Attribution ...
JWH-302 (1-pentyl-3-(3-methoxyphenylacetyl)indole) is an analgesic chemical from the phenylacetylindole family, which acts as a cannabinoid agonist with moderate affinity at both the CB 1 and CB 2 receptors. It is a positional isomer of the more common drug JWH-250, though it is slightly less potent with a K i of 17 nM at CB 1, compared to 11 ...
JWH-098 is a synthetic cannabinoid receptor agonist from the naphthoylindole family. It is the indole 2-methyl derivative of a closely related compound JWH-081 , but has markedly different affinity for the CB 1 and CB 2 receptors.
JWH-015 is a chemical from the naphthoylindole family that acts as a subtype-selective cannabinoid agonist. Its affinity for CB 2 receptors is 13.8 nM, while its affinity for CB 1 is 383 nM, meaning that it binds almost 28 times more strongly to CB 2 than to CB 1 . [ 1 ]
JWH-030 is a research chemical which is a cannabinoid receptor agonist. [2] It has analgesic effects and is used in scientific research. [ 3 ] It is a partial agonist at CB 1 receptors , with a K i of 87 nM, making it roughly half the potency of THC . [ 4 ]
JWH-145 (1-naphthalenyl(1-pentyl-5-phenyl-1H-pyrrol-3-yl)-methanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB 1 (K i = 14 ± 2nM) and CB 2 (K i = 6.4 ± 0.4nM) receptors, with a moderate (~2.2x) selectivity for the CB 2 receptor.
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