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Common cosolvents for this purpose are ethanol, propylene glycol, glycerine, glycofural, and polyethylene glycols. [7] The effect of cosolvency on drug solubilization can be great, as evidenced by a 2009 study in which researchers from Panjab University showed the solubility of various anti-diabetic drugs increase by more than 500 times by use ...
Estimates on the prevalence of propylene glycol allergy range from 0.8% (10% propylene glycol in aqueous solution) to 3.5% (30% propylene glycol in aqueous solution). [ 70 ] [ 71 ] [ 72 ] The North American Contact Dermatitis Group (NACDG) data from 1996 to 2006 showed that the most common site for propylene glycol contact dermatitis was the ...
A toy called Bindeez (Aqua Dots in North America) was recalled by the distributor in November 2007 because of the unauthorized substitution of 1,5-pentanediol with 1,4-butanediol.
Polyols may be classified according to their chemistry. [5] Some of these chemistries are polyether, polyester, [6] polycarbonate [7] [8] and also acrylic polyols. [9] [10] Polyether polyols may be further subdivided and classified as polyethylene oxide or polyethylene glycol (PEG), polypropylene glycol (PPG) and Polytetrahydrofuran or PTMEG.
Petrochemical plant in Saudi Arabia. Petrochemicals (sometimes abbreviated as petchems [1]) are the chemical products obtained from petroleum by refining. Some chemical compounds made from petroleum are also obtained from other fossil fuels, such as coal or natural gas, or renewable sources such as maize, palm fruit or sugar cane.
For example, N,N,N ′-Tributylpentanamidine is a switchable solvent, and for a volumetric ratio of compound to water of 2:1, it has a log(K ow)= 5.99, which is higher than 2.5. Ionic liquids [ 55 ] with low melting points are associated with asymmetric cations, and liquids with high melting point are associated with symmetric cations.
The available moisture determines microbial activity, physical properties, sensory properties and the rate of chemical changes, that if not controlled, are the cause of reduced shelf life. [10] Examples are dry cereal with semi-moist raisins , ice cream in a cone, chocolate , hard candy with liquid centers and cheese .
Polypropylene glycol is produced by ring-opening polymerization of propylene oxide. The initiator is an alcohol and the catalyst a base, usually potassium hydroxide. When the initiator is ethylene glycol or water the polymer is linear. With a multifunctional initiator like glycerine, pentaerythritol or sorbitol the polymer branches out ...