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[59] [137] [63] Sigma receptor activation by methamphetamine may facilitate its central nervous system stimulant effects and promote neurotoxicity within the brain. [ 59 ] [ 63 ] Dextromethamphetamine is a stronger psychostimulant , but levomethamphetamine has stronger peripheral effects, a longer half-life, and longer perceived effects among ...
Amphetamine-type stimulants in general are sympathomimetic amine that stimulates the central nervous system, also proven to cause insomnia, arousal, and reduced hunger. Due to its physiological and psychological effects, ATS has been used to suppress appetite, improve cognitive performance, as well as treating ADHD, depression, and narcolepsy.
MDMA was also found to have effects on blood sugar levels comparable to high doses of ephedrine. Oberlin concluded that the effects of MDMA were not limited to the sympathetic nervous system. Research was stopped "particularly due to a strong price increase of safrylmethylamine", which was still used as an intermediate in methylhydrastinine ...
[1] [2] Besides subjective effects, (R)-MDMA increased heart rate, blood pressure, and body temperature similarly to MDMA and (S)-MDMA, though it was less potent in producing these effects. [2] Body temperature was notably increased to the same extent with ( R )-MDMA 250 mg as with MDMA 125 mg and ( S )-MDMA 125 mg. [ 2 ]
[3] [4] [5] Methamphetamine psychosis, or long-term effects of stimulant use in the brain (at the molecular level), depend upon genetics and may persist for months or years. [6] Psychosis may also result from withdrawal from stimulants, particularly when psychotic symptoms were present during use.
addictive drug – psychoactive substances that with repeated use are associated with significantly higher rates of substance use disorders, due in large part to the drug's effect on brain reward systems; dependence – an adaptive state associated with a withdrawal syndrome upon cessation of repeated exposure to a stimulus (e.g., drug intake)
Klag was a passenger in a car involved in a traffic stop and was arrested for allegedly failing to appear on traffic charges. She was found to be carrying "small bags of methamphetamines on and in her body," according to KKTV. The cause of death was cardiac arrest. Jail or Agency: El Paso County Criminal Justice Center; State: Colorado
Methamphetamine is FDA approved for the treatment of ADHD and exogenous obesity. It is dispensed in the USA under the trademark name "Desoxyn" [22] and manufactured by Ovation Pharmaceuticals. [23] The levorotary form of methamphetamine, called levomethamphetamine, is an over-the-counter drug used in nasal decongestants inhalers. [24]