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A giant cell (also known as a multinucleated giant cell, or multinucleate giant cell) is a mass formed by the union of several distinct cells (usually histiocytes), often forming a granuloma. [ 1 ] Although there is typically a focus on the pathological aspects of multinucleate giant cells (MGCs), they also play many important physiological roles.
A foreign-body giant cell is a collection of fused macrophages which are generated in response to the presence of a large foreign body. This is particularly evident with catheters , parasites , or biomaterials that are inserted into the body for replacement or regeneration of diseased or damaged tissues.
Langhans giant cells (LGC) are giant cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells ( macrophages ), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery.
Adherent macrophages at the implant site can fuse into a multinucleated cell called foreign body giant cell. [11] Foreign body giant cell formation depends on the biomaterial surface properties and on the presence of interleukin-4 and interleukin-13. [11] Foreign body giant cells release reactive oxygen intermediates, degradative enzymes, and ...
Large cell is a term used in oncology. It does not refer to a particular type of cell; rather it refers to cells that are larger than would be normally expected for that type. It does not refer to a particular type of cell; rather it refers to cells that are larger than would be normally expected for that type.
Tenosynovial giant cell tumor (TGCT) is a non-malignant tumor defined histologically as inclusions of “osteoclast-like” multinucleated giant cells, hemosiderin, and macrophages. [1] This histology can present one of 2 clinically distinct ways.
Image credits: SnooBeans8816 The original thread appeared two months ago in the AskReddit community with the question: "What instantly tells you someone is a trashy parent?" As of today, it has 3 ...
Central giant-cell granuloma (CGCG) is a localised benign condition of the jaws.It is twice as common in females and is more likely to occur before age 30. Central giant-cell granulomas are more common in the anterior mandible, often crossing the midline and causing painless swellings.