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Bone pain originates from both the periosteum and the bone marrow which relay nociceptive signals to the brain creating the sensation of pain. Bone tissue is innervated by both myelinated (A beta and A delta fiber) and unmyelinated sensory neurons. In combination, they can provide an initial burst of pain, initiated by the faster myelinated ...
Exposed and necrotic bone or a fistula that probes to bone in patients with pain, infection, and one or more of the following: exposed and necrotic bone extending beyond the region of alveolar bone (i.e., inferior border and ramus in the mandible, maxillary sinus and zygoma in the maxilla) resulting in pathologic fracture, extra-oral fistula ...
Xiphodynia or Xiphoidalgia is thought to be a rare musculoskeletal syndrome that involves referred pain referred from the xiphisternal joint or the structures attached to the xiphoid process. Digital examination of the xiphoid process reproduces symptoms.
She is particularly recognized during Huey Tozoztli, the first of sequence of three festivals held in high season marking the harvest. During the festival, her priestesses designate seed corn that is to be planted in the coming season. To appease the deity, as well as to ask for good harvest, priests often engaged in child sacrifice. [5]
Other symptoms include thickening of the bone structure and accumulation of bone tissue, which both contribute to impaired joint mobility. Ligaments and cartilage can become ossified . [ 2 ] Most patients with skeletal fluorosis show side effects from the high fluoride dose such as ruptures of the stomach lining and nausea . [ 3 ]
Mechanical properties of some biomaterials and bone are summarized in Table 1. [2] Among them, hydroxyapatite is most widely studied bioactive and biocompatible material. However, it has lower Young's modulus and fracture toughness with a brittle nature. Hence, it is required to produce a biomaterial with good mechanical properties.
The uses of bisphosphonates include the prevention and treatment of osteoporosis, Paget's disease of bone, bone metastasis (with or without hypercalcemia), multiple myeloma, primary hyperparathyroidism, osteogenesis imperfecta, fibrous dysplasia, and other conditions that exhibit bone fragility.
Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. The impairment of bone metabolism causes inadequate bone mineralization.