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PFOA can be absorbed from ingestion and can penetrate skin. [16] The acid headgroup of PFOA enables binding to proteins with fatty acid or hormone substrates such as serum albumin, liver fatty acid-binding protein, and the nuclear receptors PPARα [44] and possibly CAR. [127] In animals, PFOA is mainly present in the liver, blood, and kidneys. [16]
The same goes for vitamin B12 and ferritin (a form of iron) which women may not get enough of via food, particularly those following plant-based or vegetarian diets.
Examples include PFOA and PFOS, frequently present in water-resistant textiles and sprays conferring water-resistant properties to textiles and fire-fighting foam. [3] Data from animal studies of PFOA indicate that it can cause several types of tumors and neonatal death and may have toxic effects on the immune, liver, and endocrine systems.
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Many PFAS such as PFOS and PFOA pose health and environmental concerns because they are persistent organic pollutants; they were branded as "forever chemicals" in an article in The Washington Post in 2018. [10] Some have half-lives of over eight years due to a carbon-fluorine bond, one of the strongest in organic chemistry.
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2016 The EPA "published a voluntary health advisory for PFOA and PFOS" which warned that "exposure to the chemicals at levels above 70 parts per trillion, total, could be dangerous." [71] 2016 The city of Lake Elmo, Minnesota, sued 3M a second time for polluting their drinking water with PFAS chemicals.
The best skin-care products might not always be "hypoallergenic." Here's what to know to avoid a beauty blunder in your skin-care routine. Why ‘Hypoallergenic’ Skin Care Products Can Be Dangerous