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Drospirenone is a progestin and antiandrogen medication which is used in birth control pills to prevent pregnancy and in menopausal hormone therapy, among other uses. [1] [10] It is available both alone under the brand name Slynd and in combination with an estrogen under the brand name Yasmin among others.
[15] [16] NOMAC was first introduced for medical use, for the treatment of gynecological disorders and in menopausal hormone therapy, in Europe in 1986. [1] [17] [18] It was subsequently approved in Europe in 2011 as a component of birth control pills. [1] [17] [18] NOMAC is available widely throughout the world.
Although a phase II trial for an injectable male contraceptive was halted in 2011 by an independent data safety monitoring board due likely to rare adverse effects experienced by some participants, [197] [67] leading many popular articles to suggest men could not tolerate side effects similar to those that many women endure on hormonal birth ...
[48] [51] [49] About 5 to 10% of women experience negative mood changes with combined birth control pills, and about 5% of women discontinue birth control pills due to such changes. [ 52 ] [ 48 ] A study of about 4,000 women found that progestogen-only birth control with depot medroxyprogesterone acetate had an incidence of depression of 1.5% ...
[81] [82] [83] [53] [84] A dosage of oral norethisterone of 25 mg/day for 3 weeks in men has been reported to suppress testosterone levels by about 70%, to 100 to 200 ng/dL, within 4 or 5 days, as well as to suppress sperm count and to have no effect on libido or erectile function over this short time period.
Diagram showing the site of injection of the product Vasalgel, a vasectomy alternative. Reversible inhibition of sperm under guidance (RISUG), formerly referred to as the synthetic polymer styrene maleic anhydride (SMA), is the development name of a male contraceptive injection developed at IIT Kharagpur in India by the team of Dr. Sujoy K. Guha.
Over 60 years after it was first introduced on the NHS, the pill is the main form of contraception for nearly a third of women of reproductive age in the UK, and more than 150 million women use it ...
MPA is the most widely used progestin in menopausal hormone therapy and in progestogen-only birth control. [17] [18] DMPA is approved for use as a form of long-acting birth control in more than 100 countries. [19] [20] In 2022, it was the 276th most commonly prescribed medication in the United States, with more than 800,000 prescriptions. [21] [22]
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