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This lower-than-normal B12 profile persisted throughout life in the brain tissues of patients with autism. These deficiencies are not visible by conventional blood sampling. [104] [105] As for the classic deficiency of vitamin B12, it would affect up to 40% of the population, its prevalence has not yet been studied in autism spectrum disorders ...
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
Specifically, proponents of the imprinted brain hypothesis propose that autism spectrum disorders are caused by paternal overimprinting, while schizophrenia spectrum disorders are caused by maternal overimprinting; they point to a number of supposed correlations and anticorrelations seen between the disorders and other traits to support the ...
Iryna Spodarenko / GettyWe’ve come a long way in our understanding of autism since it was first used as a clinical description in 1943. Scientists have identified some of the genes that seem to ...
The amygdala, cerebellum, and many other brain regions have been implicated in autism. [15]Unlike some brain disorders which have clear molecular hallmarks that can be observed in every affected individual, such as Alzheimer's disease or Parkinson's disease, autism does not have a unifying mechanism at the molecular, cellular, or systems level.
Rett syndrome brain samples and autism brain samples show immaturity of dendrite spines and reduction of cell-body size due to errors in coupled regulation between MECP2 and EGR2. [62] However, because of the multigene involvement in autism, the MECP2 gene has only been identified as a vulnerability factor in autism. [63]
An autistic spectrum [16] – in its simplest form this joins autism and Asperger syndrome, and can additionally include other pervasive developmental disorders (PDD). These include PDD 'not otherwise specified' (including 'atypical autism'), as well as Rett syndrome and childhood disintegrative disorder (CDD). The first three of these ...
Disorders formerly considered distinct, but now diagnosed as autism spectrum disorder, include: Asperger syndrome – a previously diagnosed form of autism often applied to people with a higher IQ who can have a less difficult time communicating with others and understanding concepts or phrases than other individuals with more severe autism. As ...