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Tirzepatide added years to my life and I’m more confident than ever. After officially hitting my goal weight, it took a month to completely wean off the medication by August 2023.
Tirzepatide is the active ingredient in the brand-name drugs Mounjaro® and Zepbound®. Mounjaro is FDA-approved as a diabetes drug but is also prescribed off-label for weight loss, while Zepbound ...
The most frequently observed are nausea, diarrhea, and vomiting, which increased in incidence with the dosage amount (that is, the higher the dose, the higher the likelihood of side-effects). The number of patients who discontinued taking tirzepatide also increased as the dosage increased, with patients taking 15 mg having a 25% discontinuation ...
GLP-1 drugs used for weight loss involve all kinds of side effects—good and not-so-good—that may or may not strike the average user. (Reminder that there are many of these meds now.
Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
More selective drugs—some are in development that act only in peripheral tissues, not the brain—may be able to achieve this result with fewer adverse effects. [12] [13] GLP-1 agonists such as tirzepatide, semaglutide, and liraglutide slow gastric emptying and also have neurologically driven effects on appetite. [14]
Eli Lilly’s drug tirzepatide, sold under the names Mounjaro for diabetes and Zepbound for weight loss, improved symptoms in heart failure patients with obesity, the company said Thursday.
Common side effects include low blood sugar, nausea, dizziness, abdominal pain, and pain at the site of injection. [6] [10] Gastrointestinal side-effects tend to be strongest at the beginning of treatment period and subside over time. [10] Other serious side effects may include angioedema, pancreatitis, gallbladder disease, and kidney problems. [6]