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Fifth disease, also known as erythema infectiosum and slapped cheek syndrome, [3] is a common and contagious disease caused by infection with parvovirus B19. [4] This virus was discovered in 1975 and can cause other diseases besides fifth disease. [5] Fifth disease typically presents as a rash and is most common in children.
Arthralgias and arthritis are commonly reported in association with parvovirus B19 infection in adults in the absence of skin findings, whereas erythema infectiosum is the main symptom observed in children. The occurrence of arthralgia coincides with the initial detection of circulating IgM- and IgG-antibodies against the viral structural ...
The Centers for Disease Control and Prevention (CDC) last week issued a health advisory on the seasonal respiratory virus, also called fifth disease or erythema infectiosum.
Erythema (Ancient Greek: ἐρύθημα, from Greek erythros 'red') is redness of the skin or mucous membranes, caused by hyperemia (increased blood flow) in superficial capillaries. [1] It occurs with any skin injury, infection, or inflammation .
Erythema infectiosum, identified as a distinct condition in 1896. [13] "fifth disease" parvovirus B19: Confluent erythematous and edematous patches on cheeks ("slapped cheek") for 1-4 days followed by a "lacy," reticular, erythematous rash on the body. Roseola infantum (exanthem subitum) "sixth disease" HHV-6 and HHV-7
The name "sixth disease" comes from its place on the standard list of rash-causing childhood diseases, which also includes measles (first), scarlet fever (second), rubella (third), Dukes' disease (fourth, but is no longer widely accepted as distinct from scarlet fever), and erythema infectiosum (fifth). [3]
The class Quintoviricetes takes the first part of its name from the Galician word quinto, meaning fifth, referring to fifth disease (erythema infectiosum) caused by parvovirus B19, and viricetes, the suffix used for virus classes. [17]
Children are more affected than adults, and immunity appears to last several years after infection. [7] Patients with TAC due to Parvovirus B19 are less likely to have the typical slapped-cheek rash (erythema infectiosum) characteristic of this infection.