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Distributed manufacturing (DM) is a production model that decentralizes manufacturing processes, enabling products to be designed, produced, and distributed closer to end-users. This shift from centralized production to localized networks offers advantages such as increased flexibility, cost efficiency, and local empowerment.
The criteria of "minimal manipulation" are variative in different countries. European regulations, according to the Reflection Paper on the classification of advanced therapy medicinal products of the European Medicines Agency, define "minimal manipulation" as the procedure that does not change biological characteristics and functions of cells. [5]
Besides the commercial vendors there are plenty of free GDSII utilities. These free tools include editors, [3] [4] [5] viewers, [6] utilities to convert the 2D layout data into common 3D formats, [7] [8] utilities to fly through a 3D version, [9] utilities to convert the binary format to a human readable ASCII format [10] and program libraries ...
Cell therapy (also called cellular therapy, cell transplantation, or cytotherapy) is a therapy in which viable cells are injected, grafted or implanted into a patient in order to effectuate a medicinal effect, [1] for example, by transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or ...
The openness of "open manufacturing" may relate to the nature of the product (open design), to the nature of the production machines and methods (e.g. open source 3D-printers, open source CNC), to the process of production and innovation (commons-based peer production / collaborative / distributed manufacturing), or to new forms of value creation (network-based bottom-up or hybrid versus ...
When a new biopharmaceutical is developed, the company will typically apply for a patent, which is a grant to exclusive manufacturing rights. This is the primary means by which the drug developer can recover the investment cost for development of the biopharmaceutical.
Biomanufacturing (or bioproduction) is a type of manufacturing or biotechnology that utilizes biological systems to produce commercially important biomaterials and biomolecules for use in medicines, food and beverage processing, and industrial applications.
Cellular manufacturing is a process of manufacturing which is a subsection of just-in-time manufacturing and lean manufacturing encompassing group technology. The goal of cellular manufacturing is to move as quickly as possible, make a wide variety of similar products, while making as little waste as possible.