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Acetamide (systematic name: ethanamide) is an organic compound with the formula CH 3 CONH 2. It is an amide derived from ammonia and acetic acid . It finds some use as a plasticizer and as an industrial solvent. [ 5 ]
The Monsanto process is an industrial method for the manufacture of acetic acid by catalytic carbonylation of methanol. [1] The Monsanto process has largely been supplanted by the Cativa process , a similar iridium -based process developed by BP Chemicals Ltd , which is more economical and environmentally friendly.
The chemical reactions of dimethylacetamide are typical of N,N-disubstituted amides. Hydrolysis of the acyl-N bond occurs in the presence of acids: . CH 3 CON(CH 3) 2 + H 2 O + HCl → CH 3 COOH + (CH 3) 2 NH 2 + Cl −
In the usual nomenclature, one adds the term "amide" to the stem of the parent acid's name. For instance, the amide derived from acetic acid is named acetamide (CH 3 CONH 2). IUPAC recommends ethanamide, but this and related formal names are rarely encountered. When the amide is derived from a primary or secondary amine, the substituents on ...
Acetamidine hydrochloride is synthesised in a two-step process that begins with a solution of acetonitrile in ethanol at close to 0 °C. [4] First, the mixture is treated with anhydrous hydrogen chloride in a Pinner reaction, producing crystals of acetimido ethyl ether hydrochloride: H 3 C−C≡N + C 2 H 5 OH + HCl → H 3 C−C(=NH·HCl)−OC ...
Acetanilide can be produced by reacting acetic anhydride with aniline: [7]. C 6 H 5 NH 2 + (CH 3 CO) 2 O → C 6 H 5 NHCOCH 3 + CH 3 COOH. The preparation used to be a traditional experiment in introductory organic chemistry lab classes, [8] but it has now been widely replaced by the preparation of either paracetamol or aspirin, both of which teach the same practical techniques (especially ...
The peroxide process is a method for the industrial production of hydrazine. In this process hydrogen peroxide is used as an oxidant instead of sodium hypochlorite, which is traditionally used to generate hydrazine. The main advantage of the peroxide process to hydrazine relative to the traditional Olin Raschig process is that it does not ...
For the production of Fingolimod—an immunosuppressant used to treat multiple sclerosis, numerous synthetic routes have been developed utilizing diethyl acetamidomalonate as the principal component. [11] The key step in these multistep synthesis processes involves typically the alkylation of DEAM with, for example, 4'-(2-iodoethyl ...