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Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
The tooth bud (sometimes called the tooth germ) is an aggregation of cells that eventually forms a tooth and is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [3] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [3]
It is organized into three parts: the enamel organ, the dental papilla and the dental follicle. [27] The enamel organ is composed of the outer enamel epithelium, inner enamel epithelium, stellate reticulum and stratum intermedium. [27] These cells give rise to ameloblasts, which produce enamel and the reduced enamel epithelium.
The enamel organ → purely the epithelial component; The tissues which have been derived from each of the three components are: The dental follicle → will develop to become the periodontal ligament, the cementum and the alveolar bone; The dental papilla → will develop to become the dental pulp and the dentine; The enamel organ → will ...
Histologic slide showing a tooth bud. A: enamel organ B: dental papilla C: dental follicle. The tooth germ is an aggregation of cells that eventually forms a tooth. [2] These cells are derived from the ectoderm of the first pharyngeal arch and the ectomesenchyme of the neural crest.
Enamel can be affected further by non-pathologic processes. Enamel is covered by various structures in relation to the development of tooth: Nasmyth membrane or enamel cuticle, structure of embryological origin is composed of keratin which gives rise to the enamel organ. [18] [19]
After the formation of enamel matrix, mineralisation of enamel takes place which is known as maturation. During this stage, the ameloblasts are slightly reduced in length. The stratum intermedium cells lose their cuboidal shape and assumed to be as spindle shape. During this stage, ameloblasts also exhibit microvilli at their distal extremities.
The cervical loop is the location on an enamel organ in a developing tooth where the outer enamel epithelium and the inner enamel epithelium join. The cervical loop is a histologic term indicating a specific epithelial structure at the apical side of the tooth germ, consisting of loosely aggregated stellate reticulum in the center surrounded by ...