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The HSE value pair (up and down) of the example above is (3,5). Half Sphere exposure (HSE) is a protein solvent exposure measure that was first introduced by Hamelryck (2005) . [ 1 ] Like all solvent exposure measures it measures how buried amino acid residues are in a protein .
An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health.
The intention of the Regulations is to reduce the risk of a fatality or serious injury resulting from a "dangerous substance" igniting and potentially exploding. Examples of a "dangerous substance", as defined by DSEAR, include sawdust, ethanol vapours, and hydrogen gas. The regulation is enforceable by the HSE or local authorities.
The threshold limit value (TLV) is a level of occupational exposure to a hazardous substance where it is believed that nearly all healthy workers can repeatedly experience at or below this level of exposure without adverse effects.
An example SDS, including guidance for handling a hazardous substance and information on its composition and properties. A safety data sheet (SDS), [1] material safety data sheet (MSDS), or product safety data sheet (PSDS) is a document that lists information relating to occupational safety and health for the use of various substances and products.
For example, in 2000, Salford City Council were fined £115,000 for a breach of the regulations. [ 10 ] It is a defence that the responsible person was not aware of the event requiring reporting or notification and that he had taken all reasonable steps to have such events brought to his notice (reg.11).
The Occupational Safety and Health Administration (U.S. OSHA) has set OSHA-STELs for 1,3-butadiene, [1] benzene [2] and ethylene oxide. [3] For chemicals, STEL assessments are usually done for 15 minutes and expressed in parts per million (ppm), or sometimes in milligrams per cubic meter (mg/m 3 ).
One point of possible objection interests the uncertainties associated with a PSA. The PSA (Probabilistic Safety Assessment) has often no associated uncertainty, though in metrology any measure shall be related to a secondary measurement uncertainty, and in the same way any mean frequency number for a random variable shall be examined with the dispersion inside the set of data.