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Structural model at atomic resolution of bacteriophage T4 [1] The structure of a typical myovirus bacteriophage Anatomy and infection cycle of bacteriophage T4. A bacteriophage (/ b æ k ˈ t ɪər i oʊ f eɪ dʒ /), also known informally as a phage (/ ˈ f eɪ dʒ /), is a virus that infects and replicates within bacteria and archaea.
In molecular biology, bacteriophage scaffolding proteins are proteins involved in bacteriophage assembly. The assembly of a macromolecular structure proceeds via a specific pathway of ordered events and involves conformational changes in the proteins as they join the assembly.
The structure of a typical bacteriophage. Bacteriophages are viruses that infect bacteria and archaea. [76] They are important in marine ecology: as the infected bacteria burst, carbon compounds are released back into the environment, which stimulates fresh organic growth. Bacteriophages are useful in scientific research because they are ...
Tailed bacteriophage structure: (1) head, (2) tail, (3) DNA, (4) capsid, (5) collar, (6) sheath, (7) tail fibres, (8) spikes, (9) base plate. In some groups of viruses - such as the class Caudoviricetes ("tail viruses") and the genus Tupanvirus - the capsid carries an appendage called the "tail". The tail of the Caudoviricetes is usually ...
Assembled major coat protein subunits in Ff (fd, f1, M13) filamentous bacteriophage (genus Inovirus), exploded view. Filamentous phage virion--schematic views. Filamentous bacteriophages are among the simplest living organisms known, with far fewer genes than the classical tailed bacteriophages studied by the phage group in the mid-20th century.
However, some tailed bacteriophage genomes can vary quite significantly in nucleotide sequence, even among the same genus. Due to their characteristic structure and possession of potentially homologous genes, it is believed these bacteriophages possess a common origin. [2]
Schematic drawing of a Φ29 phage virion (cross section and side view). The structure of Φ29 is composed of seven main proteins: the terminal protein (p3), the head or capsid protein (p8), the head or capsid fiber protein (p8.5), the distal tail knob (p9), the portal or connector protein (p10), the tail tube or lower collar proteins (p11), and the tail fibers or appendage proteins (p12*).
Structure of phage ΦX174 capsid Schematic drawing of a Sinsheimervirus (aka Phix174microvirus) virion. The phi X 174 (or ΦX174) bacteriophage is a single-stranded DNA virus that infects Escherichia coli.