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Flibanserin, sold under the brand name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD). [4] [5] The medication improves sexual desire, increases the number of satisfying sexual events, and decreases the distress associated with low sexual desire. [6]
After evaluating symptom severity using the scales, patients are then prescribed different types of drugs. Flibanserin [1] and Bremelanotide [3] were developed for raising sexual desire in women, whereas similar conditions in men are treated using medications for sexual dysfunction. [4]
One of the phase 3 trials was a randomized, double-blind placebo-controlled trial in 826 post-menopausal women. [15] The trial patients were required to have one or more symptom of vulvovaginal atrophy (VVA) that was moderate or severe in nature with fewer than 5% of cells that were superficial when examined by a vaginal smear and a vaginal pH ...
Hormone replacement therapy (HRT), also known as menopausal hormone therapy or postmenopausal hormone therapy, is a form of hormone therapy used to treat symptoms associated with female menopause. [ 1 ] [ 2 ] Effects of menopause can include symptoms such as hot flashes , accelerated skin aging, vaginal dryness , decreased muscle mass , and ...
After menopause the vaginal epithelium changes and becomes a few layers thick. [18] Many of the signs and symptoms that accompany menopause occur in atrophic vaginitis. [3] The earliest symptoms of atrophic vaginitis may be decreased vaginal lubrication, while other symptoms may appear later. [14] Genitourinary symptoms include dryness [3] [19 ...
Bremelanotide, sold under the brand name Vyleesi, is a medication used to treat low sexual desire in women. [2] Specifically it is used for low sexual desire which occurs before menopause and is not due to medical problems, psychiatric problems, or problems within the relationship.
Menopause is a natural decline in the ovarian function of women who reach the age between 45 and 54 years. "About 25 million women pass through menopause worldwide each year, and it has been estimated that, by the year 2030, the world population of menopausal and postmenopausal women will be 1.2 billion, with 47 million new entrants each year."
In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system. Hypoestrogenism is most commonly found in women who are postmenopausal, have primary ovarian insufficiency (POI), or are presenting with amenorrhea (absence of menstrual periods).
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