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Both newer and older drugs are generally equally effective in new onset epilepsy. [42] The newer drugs tend to have fewer side effects. [42] For newly diagnosed partial or mixed seizures, there is evidence for using gabapentin, lamotrigine, oxcarbazepine or topiramate as monotherapy. [42]
The adverse effects found in the Phase II trial mainly affected the central nervous system, and appeared to be dose-related. [8] The most common adverse effects were drowsiness, dizziness, tinnitus and vertigo, confusion, and slurred speech. [9] Less common side effects included tremor, memory loss, gait disturbances, and double vision. [10]
Oxcarbazepine is an anticonvulsant used to reduce the occurrence of epileptic episodes, and is not intended to cure epilepsy. [12] Oxcarbazepine is used alone or in combination with other medications for the treatment of focal (partial) seizures in adults. [3]
The anticonvulsant effects of diazepam can help in the treatment of seizures due to a drug overdose or chemical toxicity as a result of exposure to sarin, VX, or soman (or other organophosphate poisons), lindane, chloroquine, physostigmine, or pyrethroids.
Levetiracetam, sold under the brand name Keppra among others, is a novel antiepileptic drug [7] used to treat epilepsy. [8] It is used for partial-onset, myoclonic, or tonic–clonic seizures, [7] and is taken either by mouth as an immediate or extended release formulation or by injection into a vein.
The mainstay treatment of epilepsy is anticonvulsant medications, possibly for the person's entire life. [26] The choice of anticonvulsant is based on seizure type, epilepsy syndrome, other medications used, other health problems, and the person's age and lifestyle. [ 147 ]
Temporal lobe epilepsy is the most common type of focal onset epilepsy among adults. [1] Seizure symptoms and behavior distinguish seizures arising from the mesial temporal lobe from seizures arising from the lateral (neocortical) temporal lobe. [2] Memory and psychiatric comorbidities may occur.
Felbamate (marketed under the brand name Felbatol by MedPointe) is an anticonvulsant [2] used in the treatment of epilepsy.It is used to treat partial seizures [3] [4] (with and without generalization) in adults and partial and generalized seizures associated with Lennox–Gastaut syndrome in children.