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Acute GPP typically requires inpatient management including both topical and systemic therapy, and supportive measures. [3] Systemic glucocorticoid withdrawal is a common causative agent. [ 4 ] Withdrawal or administration of certain drugs in the patient's previous medication regimen may be required.
Generalized pustular psoriasis (GPP) is a rare type of psoriasis that can present in a variety of forms. [1] Unlike the most general and common forms of psoriasis, GPP usually covers the entire body and with pus-filled blisters rather than plaques. GPP can present at any age, but is rarer in young children.
APP tends to occur in women more frequently than in men, and is usually less severe than other forms of generalized pustular psoriasis such as impetigo herpetiformis. [6] This form of psoriasis is characterized by ring-shaped plaques with pustules around the edges and yellow crusting. [6] APP most often affects the torso, neck, arms, and legs. [6]
The skin under and surrounding the pustules is red and tender. [17] Pustular psoriasis can either be localized or more widespread throughout the body. Two types of localized pustular psoriasis include psoriasis pustulosa palmoplantaris and acrodermatitis continua of Hallopeau; both forms are localized to the hands and feet.
Pustulosis is highly inflammatory skin condition resulting in large fluid-filled blister-like areas - pustules. Pustulosis typically occurs on the palms of the hands and/or the soles of the feet. The skin of these areas peels and flakes . [1]
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Pustule: A pustule is a small elevation of the skin usually consisting of necrotic inflammatory cells. [30] Cyst: A cyst is an epithelial-lined cavity. [10] Wheal: A wheal is a rounded or flat-topped, pale red papule or plaque that is characteristically evanescent, disappearing within 24 to 48 hours.
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