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Hydroxyapatite (IMA name: hydroxylapatite [5]) (Hap, HAp, or HA) is a naturally occurring mineral form of calcium apatite with the formula Ca 5 (PO 4) 3 (OH), often written Ca 10 (PO 4) 6 (OH) 2 to denote that the crystal unit cell comprises two entities. [6] It is the hydroxyl endmember of the complex apatite group.
The human body is composed of approximately: 64% water, 20% protein, 10% fat, 1% carbohydrate, 5% minerals. [1] The decomposition of soft tissue is characterized by the breakdown of these macromolecules, and thus a large proportion of the decomposition products should reflect the amount of protein and fat content initially present in the body. [4]
Amorphous calcium phosphate in combination with casein phosphopeptide has been used as a dental treatment to treat incipient dental decay. ACP sees its main use as an occluding agent, which aids in reducing sensitivity. Studies have shown that it does form a remineralized phase of hydroxyapatite consistent with the natural enamel.
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
Altitude decompression is the natural consequence of unprotected ascent to high altitude, while hypobaric decompression is due to intentional or unintentional release of pressurisation of a pressure suit or pressurised compartment, vehicle or habitat, and may be controlled or uncontrolled, and includes decompression in preparation for space ...
This can be done in terms of the chemical elements present, or by molecular structure e.g., water, protein, fats (or lipids), hydroxyapatite (in bones), carbohydrates (such as glycogen and glucose) and DNA. In terms of tissue type, the body may be analyzed into water, fat, connective tissue, muscle, bone, etc.
Phosphate minerals are minerals that contain the tetrahedrally coordinated phosphate (PO 3− 4) anion, sometimes with arsenate (AsO 3− 4) and vanadate (VO 3− 4) substitutions, along with chloride (Cl −), fluoride (F −), and hydroxide (OH −) anions, that also fit into the crystal structure.
Mineralization in which the calcium phosphate layer gradually transforms into crystalline hydroxyapatite, that mimics the mineral phase naturally contained with vertebrate bones. Later, it was discovered that the morphology of the gel surface layer was a key component in determining the bioactive response.