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Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [ 1 ] As of 2024 [update], the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [ 2 ][ 3 ] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from ...
For over 90 years, hematopoietic stem cell transplantation (HSCT) has been used to treat people with conditions such as leukaemia and lymphoma; this is the only widely practiced form of stem-cell therapy. [95] [98] [99] As of 2016, the only established therapy using stem cells is hematopoietic stem cell transplantation. [100]
Induced pluripotent stem cells (also known as iPS cells or iPSCs) are a type of pluripotent stem cell that can be generated directly from a somatic cell. The iPSC technology was pioneered by Shinya Yamanaka and Kazutoshi Takahashi in Kyoto, Japan, who together showed in 2006 that the introduction of four specific genes (named Myc, Oct3/4, Sox2 ...
Mesenchymal stem cells (MSCs) also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue). [1 ...
Stem cells are cells found in all multi-cellular organisms. They were isolated in mice in 1981, and in humans in 1998. [1] In humans there are many types of stem cells, each with varying levels of potency. Potency is a measure of a cell's differentiation potential, or the number of other cell types that can be made from that stem cell.
Introduction. Somatic cell nuclear transfer is a technique for cloning in which the nucleus of a somatic cell is transferred to the cytoplasm of an enucleated egg. After the somatic cell transfers, the cytoplasmic factors affect the nucleus to become a zygote. The blastocyst stage is developed by the egg to help create embryonic stem cells from ...
Regenerative medicine. A colony of human embryonic stem cells. Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". [1] This field holds the promise of engineering damaged tissues and organs by stimulating the body's own repair ...
A stem cell possesses two properties: . Self-renewal is the ability to go through numerous cycles of cell division while still maintaining its undifferentiated state. Stem cells can replicate several times and can result in the formation of two stem cells, one stem cell more differentiated than the other, or two differentiated cells.
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