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  2. Armodafinil - Wikipedia

    en.wikipedia.org/wiki/Armodafinil

    A Cephalon-founded study in which patients were administered modafinil, methylphenidate, and a placebo found that modafinil produces "psychoactive and euphoric effects and feelings consistent with [methylphenidate]." [12] Like modafinil, armodafinil is an inhibitor and/or inducer of certain cytochrome P450 enzymes.

  3. Modafinil - Wikipedia

    en.wikipedia.org/wiki/Modafinil

    In a later large phase 3 clinical trial of modafinil for adult ADHD, modafinil was not effective in improving symptoms, there was also a high rate of side effects (86%) and discontinuation (47%). [248] The poor tolerability of modafinil in this study was possibly due to the use of high doses (210–510 mg/d). [248]

  4. Guanfacine - Wikipedia

    en.wikipedia.org/wiki/Guanfacine

    Guanfacine was first described by 1974 [12] and was approved for medical use in the United States in 1986. [10] It is available as a generic medication. [10] In 2022, it was the 275th most commonly prescribed medication in the United States, with more than 800,000 prescriptions.

  5. Eugeroic - Wikipedia

    en.wikipedia.org/wiki/Eugeroic

    Eugeroics, in the sense of modafinil-type wakefulness promoting agents, include modafinil itself, armodafinil, and adrafinil, among others. [9] They are medically indicated for the treatment of certain sleep disorders , including excessive daytime sleepiness (EDS) in narcolepsy or obstructive sleep apnea (OSA).

  6. List of modafinil analogues and derivatives - Wikipedia

    en.wikipedia.org/wiki/List_of_modafinil...

    [3] [2] [4] The modafinil analogues are of interest in the potential treatment of a condition involving the misuse of stimulant drugs (psychostimulant use disorder or PSUD), as drugs that help increase motivation (pro-motivational agents) to treat motivational disorders, [4] [5] [6] and for treatment of neurodegenerative diseases such as ...

  7. Management of attention deficit hyperactivity disorder

    en.wikipedia.org/wiki/Management_of_attention...

    Attention deficit hyperactivity disorder management options are evidence-based practices with established treatment efficacy for ADHD.Approaches that have been evaluated in the management of ADHD symptoms include FDA-approved pharmacologic treatment and other pharmaceutical agents, psychological or behavioral approaches, combined pharmacological and behavioral approaches, cognitive training ...

  8. Flmodafinil - Wikipedia

    en.wikipedia.org/wiki/Flmodafinil

    Flmodafinil (developmental code names CRL-40,940, NLS-4, JBG01-41), also known as bisfluoromodafinil and lauflumide, is a wakefulness-promoting agent related to modafinil which has been developed for treatment of a variety of different medical conditions.

  9. Drugs in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_pregnancy

    Opioid use is the main cause of neonatal abstinence syndrome, which is where the baby experiences withdrawals from the opioid they were exposed to during the pregnancy. Typical symptoms may include tremors, convulsions, twitching, excessive crying, poor feeding or sucking, slow weight gain, breathing problems, fever, diarrhea, and vomiting. [91]

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