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A summary from 1976 described it as: "measures used to lower the plasma lipids in patients with hyperlipidemia will lead to reductions in new events of coronary heart disease". [1] It states, more concisely, that "decreasing blood cholesterol [...] significantly reduces coronary heart disease".
The chronic endothelial injury hypothesis is one of two major mechanisms postulated to explain the underlying cause of atherosclerosis and coronary heart disease (CHD), the other being the lipid hypothesis. Although an ongoing debate involving connection between dietary lipids and CHD sometimes portrays the two hypotheses as being opposed, they ...
“Genetics is the cause of high cholesterol in almost all patients with persistently high cholesterol levels. Diet does play some role, of course, but persistently elevated high cholesterol is ...
where H is HDL cholesterol, L is LDL cholesterol, C is total cholesterol, T are triglycerides, and k is 0.20 if the quantities are measured in mg/dL and 0.45 if in mmol/L. There are limitations to this method, most notably that samples must be obtained after a 12 to 14 h fast and that LDL-C cannot be calculated if plasma triglyceride is >4.52 ...
The more cholesterol a rat eats the lower the blood cholesterol. [16] During the first seven hours after ingestion of cholesterol, as absorbed fats are being distributed around the body within extracellular water by the various lipoproteins (which transport all fats in the water outside cells), the concentrations increase.
A 2021 study linking strawberries to heart health found eating 2.5 servings of strawberries per day for four weeks improved LDL cholesterol levels in adults with obesity and high cholesterol.
Cholesterol is the dynamic "glue" that holds the raft together. [3] Due to the rigid nature of the sterol group, cholesterol partitions preferentially into the lipid rafts where acyl chains of the lipids tend to be more rigid and in a less fluid state. [6] One important property of membrane lipids is their amphipathic character.
Cardiolipin (IUPAC name 1,3-bis(sn-3’-phosphatidyl)-sn-glycerol, "sn" designating stereospecific numbering) is an important component of the inner mitochondrial membrane, where it constitutes about 20% of the total lipid composition.