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Diffuse cutaneous leishmaniasis produces widespread skin lesions which resemble leprosy, and may not heal on their own. [3] Mucocutaneous leishmaniasis causes both skin and mucosal ulcers with damage primarily of the nose and mouth. [2] [3] Visceral leishmaniasis or kala-azar ('black fever') is the most serious form and is generally fatal if ...
Leishmania / l iː ʃ ˈ m eɪ n i ə,-ˈ m æ n-/ [1] is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. [2] [3] [4] They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World.
Cutaneous leishmaniasis is the most common form of leishmaniasis affecting humans. [4] It is a skin infection caused by a single-celled parasite that is transmitted by the bite of a phlebotomine sand fly. There are about thirty species of Leishmania that may cause cutaneous leishmaniasis.
Visceral leishmaniasis (VL), also known as kala-azar (Hindi: kālā āzār, "black sickness") [2] or "black fever", is the most severe form of leishmaniasis and, without proper diagnosis and treatment, is associated with high fatality. [3] Leishmaniasis is a disease caused by protozoan parasites of the genus Leishmania.
Leishmania donovani is a species of intracellular parasites belonging to the genus Leishmania, a group of haemoflagellate kinetoplastids that cause the disease leishmaniasis. It is a human blood parasite responsible for visceral leishmaniasis or kala-azar, the most severe form of leishmaniasis.
L. tropica causes a broad spectrum of leishmaniasis forms in humans. Most common is a variant called dry-type cutaneous leishmaniasis. After an incubation period lasting more than 2 months, a small brownish nodular lesion will appear with a slowly extending plaque reaching a size of 1–2 centimetres (0.39–0.79 in) after 6 months.
[citation needed] However, when the host is infected, the Leishmania can cause 3 different forms of Leishmaniasis. For this species, it has been known to cause cutaneous leishmaniasis and mucocutaneous leishmaniasis. Cutaneous leishmaniasis is commonly characterized with skin lesions, which can appear localized, or throughout the body.
Leishmaniasis lesion on adult human forearm. One major pathogen from the phylum Euglenozoa is Leishmania. Leishmania causes leishmaniasis. The symptoms of leishmaniasis include systemic and skin/membrane damage. Leishmania parasites spread by phlebotomine sand flies in the tropics, subtropics, and southern Europe. [13]