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Finally, CYP1A1 catalyses this intermediate to form BaP-7,8-dihydrodiol-9,10-epoxide, which is a carcinogen. [9] However, an in vivo experiment with gene-deficient mice has found that the hydroxylation of benzo[a]pyrene by CYP1A1 can have an overall protective effect on the DNA, rather than contributing to potentially carcinogenic DNA ...
13078 Ensembl ENSG00000138061 ENSMUSG00000024087 UniProt Q16678 Q64429 RefSeq (mRNA) NM_000104 NM_009994 NM_001364889 RefSeq (protein) NP_000095 NP_034124 NP_001351818 Location (UCSC) Chr 2: 38.07 – 38.11 Mb Chr 17: 80.01 – 80.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. Function CYP1B1 belongs ...
1544 13077 Ensembl ENSG00000140505 ENSMUSG00000032310 UniProt P05177 P00186 RefSeq (mRNA) NM_000761 NM_009993 RefSeq (protein) NP_000752 NP_034123 Location (UCSC) Chr 15: 74.75 – 74.76 Mb Chr 9: 57.58 – 57.59 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cytochrome P450 1A2 (abbreviated CYP1A2), a member of the cytochrome P450 mixed-function oxidase system, is involved in the ...
I took my AncestryDNA test in 2019, and in the five years since, the site has continued to deepen. Every year or so, the site adds even more regions to its database, meaning your results are often ...
3815 16590 Ensembl ENSG00000157404 ENSMUSG00000005672 UniProt P10721 P05532 RefSeq (mRNA) NM_000222 NM_001093772 NM_001122733 NM_021099 RefSeq (protein) NP_000213 NP_001087241 NP_001116205 NP_066922 Location (UCSC) Chr 4: 54.66 – 54.74 Mb Chr 5: 75.74 – 75.82 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase ...
Peptidylprolyl isomerase A (PPIA), also known as cyclophilin A (CypA) or rotamase A is an enzyme that in humans is encoded by the PPIA gene on chromosome 7. [4] [5] [6] As a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, this protein catalyzes the cis-trans isomerization of proline imidic peptide bonds, which allows it to regulate many biological processes, including ...
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are generally regarded as monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol , steroids , and other lipids , including the remarkable carbon-carbon bond scission catalyzed by this enzyme.
n/a Ensembl ENSG00000170180 n/a UniProt P02724 n/a RefSeq (mRNA) NM_001308187 NM_001308190 NM_002099 n/a RefSeq (protein) NP_001295116 NP_001295119 NP_002090 n/a Location (UCSC) Chr 4: 144.11 – 144.14 Mb n/a PubMed search n/a Wikidata View/Edit Human Glycophorin A (MNS blood group), also known as GYPA, is a protein which in humans is encoded by the GYPA gene. GYPA has also recently been ...