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Naltrexone-bupropion. An FDA-approved weight loss medication, naltrexone-bupropion is generally considered effective and safe to use. You may experience side effects like dizziness, mood changes ...
Naltrexone/bupropion, sold under the brand name Contrave among others, is a fixed-dose combination medication for the management of chronic obesity in adults in combination with a reduced-calorie diet and increased physical activity. [4] [6] It contains naltrexone, an opioid antagonist, and bupropion, an aminoketone atypical antidepressant. [4]
Naltrexone-bupropion (Contrave) is a two-in-one combination that can help with weight loss. Used together these drugs may help reduce appetite and help control cravings.
A systematic review published in the journal Obesity Reviews in 2019 found that just about all of the widely-used medications for depression resulted in long-term weight gain, with the exception ...
This is not much different from the weight loss produced by several other weight-loss medications such as sibutramine or orlistat. [74] The combination drug naltrexone/bupropion has been approved by the US Food and Drug Administration (FDA) for the treatment of obesity. [75] [76]
[8] [14] Naltrexone, as naltrexone/bupropion (brand name Contrave), is also used to treat obesity. [15] It is on the World Health Organization's List of Essential Medicines . [ 16 ] In 2021, it was the 254th most commonly prescribed medication in the United States, with more than 1 million prescriptions.
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