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If TB bacteria gain entry to the blood stream from an area of damaged tissue, they can spread throughout the body and set up many foci of infection, all appearing as tiny, white tubercles in the tissues. [96] This severe form of TB disease, most common in young children and those with HIV, is called miliary tuberculosis. [97]
Medical history, such as close contact with other people with infectious mononucleosis; Physical examination, including palpation of any enlarged lymph nodes in the neck, or enlarged spleen. The heterophile antibody test is a screening test that gives results. Serological tests take longer time, but are more accurate.
A positive result indicates TB exposure. 5 mm or more is positive in An HIV-positive person; Persons with recent contacts with a TB patient; Persons with nodular or fibrotic changes on chest X-ray consistent with old healed TB; Patients with organ transplants, and other immunosuppressed patients; 10 mm or more is positive in
The medical history includes obtaining the symptoms of pulmonary TB: productive, prolonged cough of three or more weeks, chest pain, and hemoptysis.Systemic symptoms include low grade remittent fever, chills, night sweats, appetite loss, weight loss, easy fatiguability, and production of sputum that starts out mucoid but changes to purulent. [1]
The initial emphasis was on "DOT, or directly observed therapy, using a specific combination of TB medicines known as short-course chemotherapy as one of the five essential elements for controlling TB. [5] In 1993, the World Bank's Word Development Report claimed that the TB control strategies used in DOTS were one of the most cost-effective ...
Patients with MDR-TB should not be accommodated on the same ward as immunosuppressed patients (HIV-infected patients, or patients on immunosuppressive drugs). Careful monitoring of compliance with treatment is crucial to the management of MDR-TB (and some physicians insist on hospitalisation if only for this reason).
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [1] [2] First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid.
A 1994 CDC recommendation stated TB isolation rooms should be checked daily for negative pressure while being used for TB isolation. If these rooms are not being used for patients who have suspected or confirmed TB but potentially could be used for such patients, the negative pressure in the rooms should be checked monthly.
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