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Korsakoff syndrome (KS) [1] is a disorder of the central nervous system characterized by amnesia, deficits in explicit memory, and confabulation. This neurological disorder is caused by a deficiency of thiamine (vitamin B 1 ) in the brain, and it is typically associated with and exacerbated by the prolonged, excessive ingestion of alcohol . [ 2 ]
Wernicke-Korsakoff syndrome ( WKS) is the combined presence of Wernicke encephalopathy (WE) and alcoholic Korsakoff syndrome (AKS [clarification needed] ). Due to the close relationship between these two disorders, people with either are usually diagnosed with WKS as a single syndrome. It mainly causes vision changes, ataxia and impaired memory.
Wernicke encephalopathy. Wernicke encephalopathy ( WE ), also Wernicke's encephalopathy, [ 1] or wet brain is the presence of neurological symptoms caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B 1 ). [ 2] The condition is part of a larger group of thiamine ...
Korsakoff's syndrome and Wernicke–Korsakoff syndrome are particular forms of alcohol related brain injury which may be related to alcohol related dementia. [18] Many experts use the terms alcohol (or alcoholic) dementia to describe a specific form of ARD, characterized by impaired executive function (planning, thinking, and judgment).
Confabulation can occur with nervous system injuries or illnesses, including Korsakoff's syndrome, Alzheimer's disease, schizophrenia, and traumatic brain injury. It is believed that the right frontal lobe of the brain is damaged, causing false memories. Children are especially susceptible to forced confabulation as they are highly impressionable.
Alcohol withdrawal syndrome ( AWS) is a set of symptoms that can occur following a reduction in alcohol use after a period of excessive use. [ 1] Symptoms typically include anxiety, shakiness, sweating, vomiting, fast heart rate, and a mild fever. [ 1] More severe symptoms may include seizures, and delirium tremens (DTs); which can be fatal in ...
Specialty. Neurology. Wernicke's aphasia, also known as receptive aphasia, [ 1] sensory aphasia, fluent aphasia, or posterior aphasia, is a type of aphasia in which individuals have difficulty understanding written and spoken language. [ 2] Patients with Wernicke's aphasia demonstrate fluent speech, which is characterized by typical speech rate ...
Transketolase. Transketolase (abbreviated as TK) is an enzyme that, in humans, is encoded by the TKT gene. [1] It participates in both the pentose phosphate pathway in all organisms and the Calvin cycle of photosynthesis. Transketolase catalyzes two important reactions, which operate in opposite directions in these two pathways.