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Vitamin B 12 deficiency can be determined, but not always. [14] This means it measures forms of vitamin B 12 that are "active" and can be used by the body, as well as the "inactive" forms, which cannot. [151] Vitamin B 12 deficiency can be found within normal levels, so clinical symptoms should be taken into account when a diagnosis is made. [2]
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Deficiency symptoms in children include developmental delay, regression, irritability, involuntary movements and hypotonia. [34] Vitamin B 12 deficiency is most commonly caused by malabsorption, but can also result from low intake, immune gastritis, low presence of binding proteins, or use of certain medications. [6]
A feeling of pressure and squeezing in the chest is a serious indication that medical care is essential because chest pain and discomfort is one of the most common symptoms of heart attack in men.
Vitamin B 6 deficiency causes seborrhoeic dermatitis-like eruptions, pink eye and neurological symptoms (e.g. epilepsy). Vitamin B 7: Biotin: Biotin deficiency does not typically cause symptoms in adults, other than cosmetic issues such as decreased hair and nail growth, but may lead to impaired growth and neurological disorders in infants.
The signs and symptoms of niacin deficiency start to revert within days of oral supplementation with large amounts of the vitamin. [23] [24] Chronic alcoholism is a contributing risk factor. Pantothenic acid (Vitamin B 5) deficiency: Irritability, fatigue, and apathy. [25] [26] Extremely rare. Vitamin B 6 deficiency
Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B 3). [2] Symptoms include inflamed skin, diarrhea, dementia, and sores in the mouth. [1] Areas of the skin exposed to friction and radiation are typically affected first. [1] Over time affected skin may become darker, stiffen, peel, or bleed. [1] [3]
Thiamine deficiency and errors of thiamine metabolism are believed to be the primary cause of Wernicke encephalopathy. Thiamine, also called B 1, helps to break down glucose. Specifically, it acts as an essential coenzyme to the TCA cycle and the pentose phosphate shunt. Thiamine is first metabolised to its more active form, thiamine ...