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Multisystem inflammatory syndrome in children (MIS-C), or paediatric inflammatory multisystem syndrome (PIMS / PIMS-TS), or systemic inflammatory syndrome in COVID-19 (SISCoV), is a rare systemic illness involving persistent fever and extreme inflammation following exposure to SARS-CoV-2, the virus responsible for COVID-19. [7]
Multisystem inflammatory syndrome may refer to: . Multisystem inflammatory syndrome in children (also known as 'paediatric multisystem inflammatory syndrome', or 'paediatric inflammatory multisystem syndrome' - 'PIMS'), a rare life-threatening illness resembling Kawasaki disease that has been observed following exposure to the virus responsible for COVID-19; [1] [2] [3] while a similar ...
MIS Multisystem Inflammatory Syndrome MIS-A Multisystem Inflammatory Syndrome in adults MIS-C Multisystem Inflammatory Syndrome in children MJD Machado-Joseph disease: ML mucolipidoses: MLD Metachromatic leukodystrophy: MMA Monomelic amyotrophy: MMR Measles, mumps, rubella: MMRV Measles, mumps, rubella, varicella: MND Motor neuron disease: MODY
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis , in which medium-sized blood vessels become inflamed throughout the body. [ 1 ]
Post-acute infection syndromes (PAISs) or post-infectious syndromes are medical conditions characterized by symptoms attributed to a prior infection.While it is commonly assumed that people either recover or die from infections, long-term symptoms—or sequelae—are a possible outcome as well. [1]
[8] During the COVID-19 pandemic, Grupp collaborated with various researchers on "MIS-C different from severe COVID-19 in children." The study found that Multisystem inflammatory syndrome in children is a post-infectious syndrome distinct from Kawasaki disease and may help guide treatment decisions. [11]
It encompasses a spectrum of three clinically overlapping autoinflammatory syndromes including familial cold autoinflammatory syndrome (FCAS, formerly termed familial cold-induced urticaria), the Muckle–Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease (NOMID, also called chronic infantile neurologic cutaneous and ...
Neonatal-onset multisystem inflammatory disease is a rare genetic periodic fever syndrome which causes uncontrolled inflammation in multiple parts of the body starting in the newborn period. Symptoms include skin rashes, severe arthritis , and chronic meningitis leading to neurologic damage.