Search results
Results from the WOW.Com Content Network
2878 14778 Ensembl ENSG00000211445 ENSMUSG00000018339 UniProt P22352 P46412 RefSeq (mRNA) NM_002084 NM_001329790 NM_001083929 NM_008161 NM_001329860 RefSeq (protein) NP_001316719 NP_002075 NP_001316789 NP_032187 Location (UCSC) Chr 5: 151.02 – 151.03 Mb Chr 11: 54.79 – 54.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Glutathione peroxidase 3 (GPx-3), also known as plasma ...
Peroxisomes owe their name to hydrogen peroxide-generating and scavenging activities. They perform key roles in lipid metabolism and the reduction of reactive oxygen species. [4] Peroxisomes are involved in the catabolism of very long chain fatty acids, branched chain fatty acids, bile acid intermediates (in the liver), D-amino acids, and ...
A peroxisome is a type of microbody that functions to help the body break down large molecules and detoxify hazardous substances. It contains enzymes like oxidase, react hydrogen peroxide as a byproduct of its enzymatic reactions. Within the peroxisome, hydrogen peroxide can then be converted to water by enzymes like catalase and peroxidase.
The peroxisome is an organelle in the cell similar to the lysosome that functions to detoxify the cell. Peroxisomes contain many different enzymes, such as catalase, and their main function is to neutralize free radicals and detoxify drugs. For this reason peroxisomes are ubiquitous in the liver and kidney.
Oxidative stress mechanisms in tissue injury. Free radical toxicity induced by xenobiotics and the subsequent detoxification by cellular enzymes (termination).. Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. [1]
In eukaryotes, catalase is usually located in a cellular organelle called the peroxisome. [30] Peroxisomes in plant cells are involved in photorespiration (the use of oxygen and production of carbon dioxide) and symbiotic nitrogen fixation (the breaking apart of diatomic nitrogen (N 2) to reactive nitrogen atoms). Hydrogen peroxide is used as a ...
This detoxification pathway is the result of multiple enzymes, with superoxide dismutases catalysing the first step and then catalases and various peroxidases removing hydrogen peroxide. As with antioxidant metabolites, the contributions of these enzymes to antioxidant defenses can be hard to separate from one another, but the generation of ...
17117 Ensembl ENSG00000242110 ENSMUSG00000022244 UniProt Q9UHK6 O09174 RefSeq (mRNA) NM_203382 NM_001167595 NM_001167596 NM_001167597 NM_001167598 NM_014324 NM_008537 RefSeq (protein) NP_001161067 NP_055139 NP_976316 NP_032563 Location (UCSC) Chr 5: 33.99 – 34.01 Mb Chr 15: 10.98 – 11 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse α-Methylacyl-CoA racemase (AMACR, EC 5.1.99.4 ...