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Usually, people with this disorder have ataxia, mild–moderate sensorineural hearing loss, narcolepsy, and cataplexy. These symptoms start happening when an affected person is about 30 years old. [6] [7] A bit later in life, people with ADCADN start showing a decline in executive function known as dementia.
Genetic testing: Genetic testing may be recommended, especially if there is a family history of hearing loss. Nonsyndromic deafness can be caused by mutations in various genes associated with auditory function.
Congenital hearing loss is a hearing loss present at birth. It can include hereditary hearing loss or hearing loss due to other factors present either in-utero (prenatal) or at the time of birth. It can include hereditary hearing loss or hearing loss due to other factors present either in-utero (prenatal) or at the time of birth.
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Hereditary deafness is the latest condition scientists are targeting with gene therapy, which is already approved to treat illnesses such as sickle cell disease and severe hemophilia.
From a genetic standpoint, this accounts for the other 70% of cases and represents the majority of hereditary hearing loss. [25] Syndromic cases occur with disorders such as Usher syndrome , Stickler syndrome , Waardenburg syndrome , Chudley-Mccullough syndrome , Alport's syndrome , and neurofibromatosis type 2 .
For people with idiopathic sudden hearing loss, different treatment approaches have been suggested that are usually based on the suspected cause of the sudden hearing loss. Treatment approaches may include corticosteroid medications, rheological drugs, vasodilators, anesthetics, and other medications chosen based on the suspected underlying ...
Due to an even larger risk of ARIA-E, both drugs are used with greater caution, if at all, for people with two copies of the APOE-4 gene, which indicates a genetic disposition for Alzheimer’s.
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