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The cause of sarcoidosis is unknown. [2] Some believe it may be due to an immune reaction to a trigger such as an infection or chemicals in those who are genetically predisposed. [12] [13] Those with affected family members are at greater risk. [4] Diagnosis is partly based on signs and symptoms, which may be supported by biopsy. [6]
Löfgren syndrome is a type of acute sarcoidosis, [1] an inflammatory disorder characterized by swollen lymph nodes in the chest, tender red nodules on the shins, fever and arthritis. [2] It is more common in women than men, and is more frequent in those of Scandinavian , Irish , African and Puerto Rican heritage.
CT scan of the chest showing bilateral lymphadenopathy in the mediastinum due to sarcoidosis. Bilateral hilar lymphadenopathy is a bilateral enlargement of the lymph nodes of pulmonary hila. It is a radiographic term for the enlargement of mediastinal lymph nodes and is most commonly identified by a chest x-ray.
Sarcoidosis is a disease of unknown cause that leads to the development of granulomas in various organs. While the lungs are typically involved, other organs may equally be affected. Some subforms of sarcoidosis, such as Löfgren syndrome, may have a particular precipitant and have a specific course. It is unknown which characteristics ...
Like hypocalcemia, hypercalcemia can be non-severe and present with no symptoms, or it may be severe, with life-threatening symptoms. Hypercalcemia is most commonly caused by hyperparathyroidism and by malignancy, and less commonly by vitamin D intoxication, familial hypocalciuric hypercalcemia and by sarcoidosis. [2]
Murray indicated that fibrosis of the lungs caused by asbestos dust was a plausible cause of the patient's death. [ 30 ] [ 31 ] The death of English textile worker Nellie Kershaw in 1924 from pulmonary asbestosis was the first case to be described in medical literature, and the first published account of disease definitely attributed to ...
“The most essential thing is, if someone is living with HIV, they’re on medication daily, medication for life. They have to be able to get those medications from their clinic,” the worker ...
The most common organ affected by aspergilloma is the lung. Aspergilloma mainly affects people with underlying cavitary lung disease such as tuberculosis, sarcoidosis, bronchiectasis, cystic fibrosis and systemic immunodeficiency. Aspergillus fumigatus, the most common causative species, is typically inhaled as small (2 to 3 micron) spores.