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  2. Melanotan II - Wikipedia

    en.wikipedia.org/wiki/Melanotan_II

    Melanotan II acts as a non-selective agonist of the melanocortin receptors MC 1, MC 3, MC 4, and MC 5. [4]Melanotan II produces melanogenesis by activation of the MC 1 receptor, whereas its clinically documented sexual effects are thought to be related to its ability to activate the MC 4 receptor (though the MC 3 is thought to also possibly be involved).

  3. α-Melanocyte-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Α-melanocyte-stimulating...

    They include afamelanotide (melanotan) and melanotan II, the former of which has been approved as a treatment to reduce photosensitivity in erythropoietic protoporphyria in the United States. [3] Bremelanotide , another analogue of α-MSH, is available in the United States not as a photoprotective agent, but for the treatment of hypoactive ...

  4. Afamelanotide - Wikipedia

    en.wikipedia.org/wiki/Afamelanotide

    A number of products are sold online and in gyms and beauty salons as "melanotan" or "melanotan-1" which discuss afamelanotide in their marketing. [17] [18] [19] Without a prescription, these drugs are not legally sold in many jurisdictions and are potentially dangerous. [20] [21] [22] [23]

  5. Atumelnant - Wikipedia

    en.wikipedia.org/wiki/Atumelnant

    Atumelnant (developmental code name CRN04894) is an investigational new drug developed by Crinetics Pharmaceuticals for the treatment of adrenocorticotropic hormone (ACTH)-dependent endocrine disorders.

  6. Melanocyte-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Melanocyte-stimulating_hormone

    The melanocyte-stimulating hormones, known collectively as MSH, also known as melanotropins or intermedins, are a family of peptide hormones and neuropeptides consisting of α-melanocyte-stimulating hormone (α-MSH), β-melanocyte-stimulating hormone (β-MSH), and γ-melanocyte-stimulating hormone (γ-MSH) that are produced by cells in the pars intermedia of the anterior lobe of the pituitary ...

  7. Melanotan - Wikipedia

    en.wikipedia.org/wiki/Melanotan

    Melanotan may refer to one of two separate peptides: . Afamelanotide, originally developed under the names "Melanotan", "Melanotan-1", or "Melanotan I" for skin tanning, a drug currently available for prescription for certain light related skin indications and also in trials in implant form as a prophylactic treatment for a series of light affected skin disorders and potential skin cancer ...

  8. Melanocortin - Wikipedia

    en.wikipedia.org/wiki/Melanocortin

    At therapeutic dose levels, it activates MC1R and MC4R. [16] Setmelanotide (Imcivree) is an MC4R agonist approved for chronic weight management in patients with genetic obesity. [17] [18] Afamelanotide (Scenesse) is an MC1R agonist approved for patients with erythropoietic protoporphyria to increase pain-free light exposure. [19] Clinical trials

  9. Bremelanotide - Wikipedia

    en.wikipedia.org/wiki/Bremelanotide

    Bremelanotide is an active metabolite of melanotan II that lacks the C-terminal amide group. [17] Aside from melanotan II and endogenous melanocyte-stimulating hormones like α-MSH, other peptide analogues of the same family as bremelanotide include afamelanotide (NDP-α-MSH), modimelanotide, and setmelanotide.

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