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Thrombin (Factor IIa) (EC 3.4.21.5, fibrose, thrombase, thrombofort, topical, thrombin-C, tropostasin, activated blood-coagulation factor II, E thrombin, beta-thrombin, gamma-thrombin) is a serine protease, that converts fibrinogen into strands of insoluble fibrin, as well as catalyzing many other coagulation-related reactions.
Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein that promotes hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura , Heyde's syndrome , and possibly hemolytic–uremic ...
Thrombin demonstrates a high level of allosteric regulation. [2] Allosterism in thrombin is regulated by the exosites 1 and 2 and the sodium binding site. A recent patent review has shown that the general consensus among researchers is that allosteric inhibitors may provide a more regulatable anticoagulant. [3]
229906 Ensembl ENSG00000137947 ENSMUSG00000028271 UniProt Q00403 P62915 RefSeq (mRNA) NM_001514 NM_145546 RefSeq (protein) NP_001505 NP_663521 Location (UCSC) Chr 1: 88.85 – 88.89 Mb Chr 3: 142.47 – 142.49 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor II B (TFIIB) is a general transcription factor that is involved in the formation of the RNA polymerase II ...
December 27, 2024 at 2:22 PM (Reuters) -U.S. President-elect Donald Trump could become the first elected politician in modern history to be hosted for two state visits by the British royal family ...
3608 67781 Ensembl n/a ENSMUSG00000001016 UniProt Q12905 Q9CXY6 RefSeq (mRNA) NM_004515 NM_001267809 NM_026374 RefSeq (protein) NP_001254738 NP_004506 NP_080650 Location (UCSC) n/a Chr 3: 90.38 – 90.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin enhancer-binding factor 2 is a protein that in humans is encoded by the ILF2 gene. Function Nuclear factor of activated T ...
Ohtani struggled to make hard contact for the rest of the series, however, and that now makes a bit more sense. He went a combined 1-for-14 with no extra-base hits in Games 3, 4 and 5 after ...
Investors struggle with whether incorporating factor-based strategies is worth it, argue over which are the premier factors, debate whether factors can be timed or not, and fret about premiums ...