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Mifepristone combined with misoprostol is the preferred medication regimen for management of early pregnancy loss. While misoprostol alone can be used, the addition of a dose of mifepristone twenty-four hours before misoprostol administration improves treatment efficacy.
Mifepristone is used in more than half of all abortions in the US. The drug was first approved for use by the US Food and Drug Administration in most cases up to 10 weeks of pregnancy in 2000.
Abdominal pain, nausea, vomiting, diarrhea, fever for more than 24 hours after taking mifepristone [51] Fever of 38 °C (100.4 °F) or higher for more than 4 hours [ 51 ] Complications under 10 weeks' pregnancy are rare; according to two large reviews, bleeding requiring a blood transfusion occurred in 0.03–0.6% of women and serious infection ...
Mifepristone is one of two drugs used in medication abortion in the U.S. But mifepristone has many uses in reproductive care and in other contexts, experts say.
Examples include the progesterone receptor weak partial agonist mifepristone, the selective progesterone receptor modulator (SPRM) ulipristal acetate, and the silent antagonist aglepristone. [ 2 ] [ 3 ] In medical abortion , mifepristone is combined with a prostaglandin (e.g., gemeprost ), while ulipristal is used for emergency contraception.
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This is a nonspecific term which may refer to any number of substances or medications, ranging from herbs [1] to prescription medications. [2] Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3]
Mifepristone is one of two drugs women take in medication abortions. Is it safe?