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The advent of the first low dead space syringe occurred with the creation of 1-ml syringes designed specifically for the administration of insulin. Then amongst the scare of HIV and rising concern of other communicable diseases to healthcare workers the creation of safety syringes occurred in 1988.
The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional:
The gauge of the needle used can range from 25 gauge to 27 gauge, while the length can vary between 1 ⁄ 2-inch to 5 ⁄ 8-inch for injections using a syringe and needle. [3]: 722 For subcutaneous injections delivered using devices such as injector pens, the needle used may be as thin as 34 gauge (commonly 30–32 gauge), and as short as 3.5 ...
Hypodermic needles are normally made from a stainless-steel or Niobium tube [17] through a process known as tube drawing where the tube is drawn through progressively smaller dies to make the needle. The end of the needle is bevelled to create a sharp pointed tip, letting the needle easily penetrate the skin. [18] A hypodermic needle tip under ...
Insulin was first used as a medication in Canada by Charles Best and Frederick Banting in 1922. [85] [86] This is a chronology of key milestones in the history of the medical use of insulin. For more details on the discovery, extraction, purification, clinical use, and synthesis of insulin, see Insulin
A standard insulin syringe with needle is smaller than an injector pen. Injector pens are an alternative to the manufacture of medication for injection in vials containing either liquid or a powder to which a diluent such as sterile water is added. When a vial is used as a means of storage, the end-user must use a syringe to "draw up" or remove ...
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