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One of the most important features of chemostats is that microorganisms can be grown in a physiological steady state under constant environmental conditions. In this steady state, growth occurs at a constant specific growth rate and all culture parameters remain constant (culture volume, dissolved oxygen concentration, nutrient and product concentrations, pH, cell density, etc.).
The temperature of the fermentation medium is maintained by a cooling jacket, coils, or both. Particularly exothermic fermentations may require the use of external heat exchangers. Nutrients may be continuously added to the fermenter, as in a fed-batch system, or may be charged into the reactor at the beginning of fermentation.
Diagram showing the setup of a continuous stirred-tank reactor. The continuous stirred-tank reactor (CSTR), also known as vat-or backmix reactor, mixed flow reactor (MFR), or a continuous-flow stirred-tank reactor (CFSTR), is a common model for a chemical reactor in chemical engineering and environmental engineering.
An ideal plug flow reactor has a fixed residence time: Any fluid (plug) that enters the reactor at time will exit the reactor at time +, where is the residence time of the reactor. The residence time distribution function is therefore a Dirac delta function at τ {\displaystyle \tau } .
A fermenter, for example, is loaded with a batch of medium and microbes which constantly produces carbon dioxide that must be removed continuously. Similarly, reacting a gas with a liquid is usually difficult, because a large volume of gas is required to react with an equal mass of liquid.
Fermentation is a type of redox metabolism carried out in the absence of oxygen. [1] [2] During fermentation, organic molecules (e.g., glucose) are catabolized and donate electrons to other organic molecules. In the process, ATP and organic end products (e.g., lactate) are formed.
A fluidized bed reactor (FBR) is a type of reactor device that can be used to carry out a variety of multiphase chemical reactions. In this type of reactor, a fluid (gas or liquid) is passed through a solid granular material (usually a catalyst) at high enough speeds to suspend the solid and cause it to behave as though it were a fluid.
Liquid state fermentation is performed in tanks, which can reach 1,001 to 2,500 square metres (10,770 to 26,910 sq ft) at an industrial scale. Liquid culture is ideal for the growing of unicellular organisms such as bacteria or yeasts.