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In 1994, Stephen Crohn became the first person discovered to be completely resistant to HIV in all tests performed despite having partners infected by the virus. [3] Crohn's resistance was a result of the absence of a receptor, which prevent the HIV from infecting CD4 present on the exterior of the white blood cells.
HIV can survive at room temperature outside the body for hours if dry (provided that initial concentrations are high), [31] and for weeks if wet (in used syringes/needles). [32] However, the amounts typically present in bodily fluids do not survive nearly as long outside the body—generally no more than a few minutes if dry. [23]
HIV drug resistance poses an issue because it reduces the possible HIV medications a person can take due to cross resistance. In cross resistance, an entire class of medication is considered ineffective in lowering a patient's HIV viral load because all the drugs in a given class share the same mechanism of action. [7]
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In 2021, it was found that Vif 2 inhibits A3B (which HIV-1 does not) and that A3B is able to inhibit a Vif-less HIV-2 (but not a Vif-less HIV-1). As A3B is also implicated in hypermutation in cancer, this discovery could lead to a way to slow down cancer cells. [13] As of January 2023, no structure of Vif 2 can be found in the Protein Data Bank.
HIV has an “early and substantial” impact on aging in infected people, reports researchers at the University of California, Los Angeles. HIV Infection Quickly Speeds Up Aging, Reports New ...
Duesberg's claim that recreational drug use, rather than HIV, was the cause of AIDS has been specifically examined and found to be false. Cohort studies have found that only HIV-positive drug users develop opportunistic infections; HIV-negative drug users do not develop such infections, indicating that HIV rather than drug use is the cause of AIDS.
On a special episode (first released on September 25, 2024) of The Excerpt podcast: This year, for just the seventh time since the start of the HIV pandemic, a person was cured of the virus. That ...
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