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In 1975, Czech physicians described the results of a clinical trial [clarification needed] looking at joint pain, where the analgesic action of aspirin versus PEA was tested; both drugs were reported to enhance joint movements and decrease pain. [7] In 1970 the drug manufacturer Spofa in Czechoslovakia introduced Impulsin, a tablet dose of PEA ...
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade).
Over the years 2017–2021, the U.S. Food and Drug Administration (FDA) issued warning letters to numerous herbalism companies for illegally marketing products under "conditions that cause them to be drugs under section 201(g)(1) of the Act [21 U.S.C. § 321(g)(1)], because they are intended for use in the diagnosis, cure, mitigation, treatment ...
Mitragynine is an indole-based alkaloid and is one of the main psychoactive constituents in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom. [4] It is an opioid that is typically consumed as a part of kratom for its pain-relieving and euphoric effects.
The active ingredient, diclofenac sodium, is a nonsteroidal anti-inflammatory drug (NSAID) that temporarily blocks the production of pain-signaling chemicals called prostaglandins, treating pain ...
Many plants that grow in the American West have use in traditional and herbal medicine.. Eriogonum fasciculatum, used in treatment of headaches and diarrhea. Dandelion (Taraxacum officinale) contains a large number of pharmacologically active compounds, and has been used for centuries as an effective laxative and diuretic, and as a treatment for bile or liver problems.
However, when used in conjunction with antiretroviral treatments, the herbal treatments hypoxis and sutherlandia "may put the patients at risk for antiretroviral treatment failure, viral resistance, or drug toxicity" [37] since they interact with antiretroviral treatments and prevent the expression of CYP3A4 and P-glycoprotein.
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