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Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by Middle East respiratory syndrome–related coronavirus (MERS-CoV). [1] Symptoms may range from none, to mild, to severe depending on age and risk level. [6] [1] Typical symptoms include fever, cough, diarrhea, and shortness of breath. [1]
The virus, which causes Middle East respiratory syndrome (MERS), is a novel coronavirus that was first identified in a patient from Jeddah, Saudi Arabia on 6 June 2012. Sporadic cases, small clusters, and large outbreaks have been reported in 24 countries, with over 2,600 cases of the virus and over 900 deaths, as of 2021.
The virus MERS-CoV is a member of the beta group of coronavirus, Betacoronavirus, lineage C. MERS-CoV genomes are phylogenetically classified into two clades, clade A and B. The earliest cases were of clade A clusters, while the majority of more recent cases are of the genetically distinct clade B. [ 10 ]
An outbreak of Middle East respiratory syndrome coronavirus occurred in South Korea from May 2015 to July 2015. [5] The virus, which causes Middle East respiratory syndrome (MERS), was a newly emerged betacoronavirus that was first identified in a patient from Saudi Arabia in April 2012. From the outbreak, a total of 910 cases were infected in ...
Middle East respiratory syndrome-related coronavirus (MERS-CoV), β-CoV (identified in 2012) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), β-CoV (identified in 2019) These cause the diseases commonly called SARS, MERS, and COVID-19 respectively.
The betacoronaviruses of the greatest clinical importance concerning humans are OC43 and HKU1 (which can cause the common cold) of lineage A, SARS-CoV-1 and SARS-CoV-2 (the causes of SARS and COVID-19 respectively) of lineage B, [2] and MERS-CoV (the cause of MERS) of lineage C. MERS-CoV is the first betacoronavirus belonging to lineage C that ...
Middle East respiratory syndrome (MERS) Middle East respiratory syndrome–related coronavirus (MERS‑CoV) 2012 Discovered in Jeddah, Saudi Arabia. [36] Caused outbreaks in 2012, 2015, and 2018. Pigs Enteritis: Porcine coronavirus HKU15 (PorCov‑HKU15) 2014 Discovered in Hong Kong, China. [37] Humans Coronavirus disease 2019 (COVID‑19)
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.