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Drug-induced immune hemolytic anemia, DIIHA. Blood smear from a patient with warm autoimmune hemolytic anemia showing spherocytes, marked polychromasia and a nucleated red blood cell. Specialty: Hematology: Symptoms: Fatigue, shortness of breath, dizziness, bloody urine, jaundice, weakness, and palpitations [1] Complications
Autoimmune hemolytic anemia (AIHA) is an autoimmune disorder which occurs when antibodies directed against the person's own red blood cells (RBCs) cause them to burst , leading to an insufficient number of oxygen-carrying red blood cells in circulation . The lifetime of the RBCs is reduced from the normal 100–120 days to just a few days in ...
Other symptoms. Respiratory symptoms: May be present in patients with M pneumoniae infection. Hemoglobinuria (the passage of dark urine that contains hemoglobin), A rare symptom that results from hemolysis, this may be reported following prolonged exposure to cold, hemoglobinuria is more commonly seen in paroxysmal cold hemoglobinuria.
It is instead a diagnosis made after a thorough clinical history, documentation of common symptoms, clinical evaluation, and exclusion of all other possible conditions. [ 1 ] The diagnosis of primary Evans syndrome is made upon blood tests to confirm not only hemolytic anemia and immune thrombocytopenic purpura, but also a positive direct ...
The current (2008) diagnostic criteria for HLH are [23] 1. A molecular diagnosis consistent with HLH. These include the identification of pathologic mutations of PRF1, UNC13D, or STX11. OR 2. Fulfillment of five out of the eight criteria below: Fever (defined as a temperature >100.3 °F, >38 °C) Enlargement of the spleen
The Rome criteria are achieved and finally issued through a consensual process, using the Delphi method (or Delphi technique). The Rome Foundation process is an international effort to create scientific data to help in the diagnosis and treatment of functional gastrointestinal disorders, also known as disorders of gut-brain interaction. [22]
When ataxia is a symptom of an injury, medication or reversible medical condition, it can be improved or reversed by stopping the medication, treating the condition or healing the injury.
The diagnosis is reached on the basis of the symptoms and supported by investigations such as blood tests and sometimes other investigations. Treatment may involve symptomatic treatment with painkillers or anti-inflammatory medications, and more severe cases may require suppression of the immune system.