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Xylometazoline, also spelled xylomethazoline, is a medication used to reduce symptoms of nasal congestion, allergic rhinitis, and sinusitis. [2] It is used directly in the nose as a spray or drops. [3] Side effects include trouble sleeping, irritation of the nose, nausea, nosebleed (3%), period pain (10%) and headache (3%).
Levmetamfetamine, also known as l-desoxyephedrine or levomethamphetamine, and commonly sold under the brand name Vicks VapoInhaler among others, is an optical isomer of methamphetamine primarily used as a topical nasal decongestant. [2] It is used to treat nasal congestion from allergies and the common cold. [7]
Flunisolide nasal spray is absorbed into the circulatory system (blood). [3] Corticosteroid nasal sprays may affect the hypothalamic-pituitary-adrenal axis function in humans. [ 7 ] After obtaining the desired clinical effect, the maintenance dose should be reduced to the smallest amount required to control the symptoms.
Nasal administration: Oxytocin is effectively distributed to the brain when administered intranasally via a nasal spray, after which it reliably crosses the blood–brain barrier and exhibits psychoactive effects in humans. [39] [40] No serious adverse effects with short-term application of oxytocin with 18~40 IU (36–80 mcg) have been ...
These side effects are usually mild and transient. Some individuals may experience throat irritation or coughing when using Fluticasone furoate inhalers. Rinsing the mouth and throat with water after inhalation can help reduce these symptoms. Headache is another common side effect reported with the use of Fluticasone furoate nasal spray or ...
As noted by the FDA, the most common symptoms of propylhexedrine overdose are the following: "[r]apid heart rate, agitation, high blood pressure, chest pain, tremor, hallucinations, delusions, confusion, nausea, and vomiting." [13] The use of propylhexedrine products in manners inconsistent with their labeling has proven fatal in some cases.
It appears to be safe in pregnancy and breastfeeding. [3] [9] Ipratropium is a short-acting muscarinic antagonist, [10] which works by causing smooth muscles to relax. [3] Common side effects of nasal spray may include headache, dry nose, dry mouth or throat, nasal or throat irritation, nosebleeds, bad taste in mouth, nausea, dizziness, or ...
Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as rhinitis medicamentosa or the rebound effect. Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum.