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A recent study by the University of Southern California revealed that exposure to air pollution can harm children's learning and memory, the LA Post reports.. Ammonium nitrate, a specific ...
Hyperammonemia, or high ammonia levels, is a metabolic disturbance characterised by an excess of ammonia in the blood. Severe hyperammonemia is a dangerous condition that may lead to brain injury and death. It may be primary or secondary. Ammonia is a substance that contains nitrogen. It is a product of the catabolism of protein.
Dementia is an umbrella term for a range of conditions that affect how the brain works, reducing the ability to remember, think and reason. It mainly affects older people and gets worse over time. Health and lifestyle factors such as high blood pressure and smoking are known to increase the risk of developing dementia. [65]
[2] [6] It may be supported by blood ammonia levels, an electroencephalogram, or computer tomography (CT scan) of the brain. [4] [6] Hepatic encephalopathy is possibly reversible with treatment. [1] This typically involves supportive care and addressing the triggers of the event. [4] Lactulose is frequently used to decrease ammonia levels. [1]
Ammonia in salt water ecosystems will have similar effects on fish as ammonia in freshwater ecosystems. Another aquatic animal that is affected by increasing amounts of ammonia is coral. Coral are very important for diversity in oceans and increasing concentrations of ammonia in the water is harming the bacteria that are found on the coral. [27]
The resultant effect of this toxicity can be reduced brain energy metabolism and function. Importantly, the toxic effects of ammonia on astrocyte remodeling can be reduced through administration of L-carnitine. [89] This astrocyte remodeling appears to be mediated through ammonia-induced mitochondrial permeability transition.
GS is present predominantly in the brain, kidneys, and liver. [4] [10] GS in the brain participates in the metabolic regulation of glutamate, the detoxification of brain ammonia, the assimilation of ammonia, recyclization of neurotransmitters, and termination of neurotransmitter signals. [4] [14] GS, in the brain, is found primarily in ...
This ammonia will obviously have to be transported out of the neurons and back into the astrocytes for detoxification, as an elevated ammonia concentration has detrimental effects on a number of cellular functions and can cause a spectrum of neuropsychiatric and neurological symptoms (impaired memory, shortened attention span, sleep-wake ...