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α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1] Hydrolysis of terminal, non-reducing α- D -galactose residues in α- D -galactosides, including galactose oligosaccharides, galactomannans and galactolipids
Medications Certain medications, such as diuretics or steroids, can increase urination in our furry friends. If your dog has recently started a new medication, be aware of possible side effects.
Pegunigalsidase alfa, sold under the brand name Elfabrio, is an enzyme replacement therapy for the treatment of Fabry disease. [2] [4] It is a recombinant human α-galactosidase-A. [4] It is a hydrolytic lysosomal neutral glycosphingolipid-specific enzyme. [2] The most common side effects are infusion-related reactions, hypersensitivity and ...
When the target gene is not found in the vector, the alpha fragment gene would be active, producing the alpha fragment and allowing for B-galactosidase to gain its activity. To trace the activity of B-galactosidase a colorless analog of lactose is used, X-gal. The hydrolysis of X-gal by B-galactosidase produces galactose, a blue colored compound.
Two recombinant enzyme replacement therapies are available to functionally compensate for α-galactosidase deficiency. Agalsidase α and β are both recombinant forms of the human α-galactosidase A enzyme and both have the same amino acid sequence as the native enzyme. Agalsidase α and β differ in the structures of their oligosaccharide side ...
Alpha-galactosidase, an enzyme; Galactose-alpha-1,3-galactose, a carbohydrate also known as Galili antigen; Alpha-gal allergy This page was last edited on 26 June ...
One common method includes enzyme assays which measure the activity of neuraminidase-1 and beta-galactosidase. [4] Decreased levels in enzymatic activity indicate a deficiency in cathepsin A. A complete urinalysis can be performed to detect the presence of oligosaccharides , [ 4 ] which would pass through the urine as excess amounts accumulate ...
The systematic name of this enzyme class is D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine galactohydrolase. Other names in common use include trihexosyl ceramide galactosidase , ceramide trihexosidase , ceramidetrihexoside alpha-galactosidase , trihexosylceramide alpha-galactosidase , and ceramidetrihexosidase .