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Aspergillosis is a fungal infection of usually the lungs, [2] ... In most instances, these are less severe, and curable with effective antifungal treatment.
It is considered first line therapy for invasive mucormycosis infections, cryptococcal meningitis, and certain aspergillus and candidal infections. [11] [12] It has been a highly effective drug for over fifty years in large part because it has a low incidence of drug resistance in the pathogens it treats. This is because amphotericin B ...
Chronic pulmonary aspergillosis is a long-term fungal infection caused by members of the genus Aspergillus—most commonly Aspergillus fumigatus. [8] The term describes several disease presentations with considerable overlap, ranging from an aspergilloma [12] —a clump of Aspergillus mold in the lungs—through to a subacute, invasive form known as chronic necrotizing pulmonary aspergillosis ...
It is recommended that patients suspected to have aspergillosis to be treated with first-line therapy drugs for the disease and have treatment modified base on in vitro susceptibility testing. [5] In cases of reported non-invasive aspergillosis caused by A. alabamensis , isolates are usually recovered from sputum, tracheal aspirates, ear canal ...
Caspofungin is used in the treatment of febrile neutropenia and as "salvage" therapy for the treatment of invasive aspergillosis. [ 6 ] [ clarification needed ] Micafungin is used as prophylaxis against Candida infections in hematopoietic stem cell transplantation patients.
Infections by other fungi, including Saccharomyces, Aspergillus (as in aspergillemia, also called invasive aspergillosiis) and Cryptococcus, are also called fungemia. It is most commonly seen in immunosuppressed or immunocompromised patients with severe neutropenia, cancer patients, or in patients with intravenous catheters.
Itraconazole, sometimes abbreviated ITZ, is an antifungal medication used to treat a number of fungal infections. [7] This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. [7]
Aspergillus fumigatus is a species of fungus in the genus Aspergillus, and is one of the most common Aspergillus species to cause disease in individuals with an immunodeficiency. Aspergillus fumigatus , a saprotroph widespread in nature, is typically found in soil and decaying organic matter, such as compost heaps, where it plays an essential ...