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Arthritis Causes. Arthritis is an umbrella term referring to a group of conditions that cause inflammation in the joints. There are actually over 100 different types of arthritis. What causes ...
While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors. [1] The underlying mechanism involves the body's immune system attacking the joints. [1] This results in inflammation and thickening of the joint capsule. [1] It also affects the underlying bone and cartilage. [1]
Rheumatoid arthritis (RA) is a disorder in which the body's own immune system starts to attack body tissues. [72] The attack is not only directed at the joint but to many other parts of the body. In rheumatoid arthritis, most damage occurs to the joint lining and cartilage which eventually results in erosion of two opposing bones.
Rheumatoid arthritis and psoriatic arthritis have a different cause. Dr. Kteleh explains that both of these types of arthritis are caused by inflammation stemming from an autoimmune condition.
The inflammatory mediators of RA including cytokines, growth factors, metalloproteinases destroy articular cartilage, subchondral bone, tendons and ligaments. Destructive synovitis leads to bone erosion and causes the ligaments of the spine to become too laxed (loose), eventually resulting in cervical spinal instability (loose neck bones). [6]
Over time, cardiomyopathy causes the heart muscle to become rigid, enlarged, or weak. ... or radiation treatments. Some autoimmune disorders, such as scleroderma, lupus, and rheumatoid arthritis ...
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