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Fungemia is the presence of fungi or yeast in the blood. The most common type, also known as candidemia , candedemia , or systemic candidiasis , is caused by Candida species. Candidemia is also among the most common bloodstream infections of any kind. [ 1 ]
Amphotericin B deoxycholate is the most common treatment antifungal agent used to treat Candida infections. [4] Topical antifungal agents are commonly taken in 3 forms: oral suspension, ointment and powder. [4] Oral suspension is mainly used to treat thrush whereas ointment is directly applied onto the infected section. [4]
Candida albicans is an opportunistic pathogenic yeast [5] that is a common member of the human gut flora.It can also survive outside the human body. [6] [7] It is detected in the gastrointestinal tract and mouth in 40–60% of healthy adults.
Drug-resistant Candida auris spread ‘worrisome’ say epidemiologists A CDC warning and a fungus spreading: Everything we know about the deadly candida auris Skip to main content
Invasive candidiasis is an infection (candidiasis) that can be caused by various species of Candida yeast. Unlike Candida infections of the mouth and throat (oral candidiasis) or vagina (Candidal vulvovaginitis), invasive candidiasis is a serious, progressive, and potentially fatal infection that can affect the blood (), heart, brain, eyes, bones, and other parts of the body.
The cure-rate for this treatment is approximately 40%. Recurrences are common, causing chronic infections and spread to other areas such as skin and scalp. Blood infections might be best assessed per symptoms if other areas are involved. An experimental, but effective second-line treatment for chronic infections, is the use of boric acid.
For cutaneous infection itraconazole or terbinafine are the primary treatment with fluconazole being recommended if primary antifungals are not well tolerated. When infection is disseminated throughout the body, Amphotericin B is the drug of choice. To completely clear the fungus, the course of treatment generally lasts from 3 to 6 months. [13]
Candida albicans is one of the most commonly isolated species and can cause infections (candidiasis or thrush) in humans and other animals. In winemaking, some species of Candida can potentially spoil wines. [4] Many species are found in gut flora, including C. albicans in mammalian hosts, whereas others live as endosymbionts in insects.
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