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This particular variant of lung cancer is usually asymptomatic and is found after chest x-rays are taken for other reasons. [7] Hemoptysis is seen occasionally [7] and, in some cases, distal obstruction of bronchi by blood clots or mucus plugs produces cough and/or infection. [1] Lesions often enlarge and progress slowly, over many years. [8]
It arises from epithelial cells that line certain internal organs and skin, and produce mucin (the main component of mucus). A malignant mucinous neoplasm is called a mucinous carcinoma . For example, for ovarian mucinous tumors , approximately 75% are benign , 10% are borderline and 15% are malignant.
Surgery is the recommended treatment for localised resectable disease. [10] When the tumour is incompletely resected (positive margins) post-operative radiotherapy gives local control comparable to a complete resection (clear margins).
The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.
Blood-laced mucus from the sinus or nose area can sometimes be misidentified as symptomatic of hemoptysis (such secretions can be a sign of nasal or sinus cancer, but also a sinus infection). Extensive non-respiratory injury can also cause one to cough up blood. Cardiac causes like congestive heart failure and mitral stenosis should be ruled ...
Constitutive action of the ErbB2/ErbB3 complex also enhances cell growth. [12] The mechanism of this malignant cancer is still unclear; however, it has been found that a colon carcinoma cell known as HCC2998 causes an increase in differentiated tumor production. The reason for this increase is due to active PI3K that are converted to a SRCC ...
Ludwig Cancer Research is an international community of scientists focused on cancer research, with the goal of preventing and controlling cancer. [1] It encompasses the Ludwig Institute for Cancer Research, an international non-profit organization founded in 1971 by philanthropist Daniel K. Ludwig .
Overexpression of the mucin proteins, especially MUC1, is associated with many types of cancer. [ 5 ] [ 6 ] Although some mucins are membrane -bound due to the presence of a hydrophobic membrane-spanning domain that favors retention in the plasma membrane , most mucins are secreted as principal components of mucus by mucous membranes or are ...