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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    The monitoring of warfarin and keeping the international normalized ratio (INR) between 2.0 and 3.0, along with avoiding over and under treatment, has driven a search for an alternative. [3] [14] A naturally occurring inhibitor of factor Xa was reported in 1971 by Spellman et al. from the dog hookworm. [15]

  4. Medication package insert - Wikipedia

    en.wikipedia.org/wiki/Medication_package_insert

    Warnings - covers possible serious side effects that may occur (e.g., boxed warning) Precautions - explains how to use the medication safely including physical impairments, food (grapefruits) and drug interactions; for example "Do not drink alcohol while taking this medication" or "Do not take this medication if you are currently taking MAOI ...

  5. Nebivolol - Wikipedia

    en.wikipedia.org/wiki/Nebivolol

    Bystolic therapy is also associated with warnings regarding abrupt cessation of therapy, cardiac failure, angina and acute myocardial infarction, bronchospastic diseases, anesthesia and major surgery, diabetes and hypoglycemia, thyrotoxicosis, peripheral vascular disease, non-dihydropyridine calcium channel blockers use, as well as precautions ...

  6. Man Who Stabbed His Father 50 Times Reportedly Tells ... - AOL

    www.aol.com/man-stabbed-father-50-times...

    Jeffrey Goedde, 41, handed himself into the Jefferson County Sheriff’s Office on Wednesday, Dec. 18, according to court documents seen by PEOPLE

  7. Should You Stop Drinking Coffee Every Day? Experts Weigh In - AOL

    www.aol.com/stop-drinking-coffee-every-day...

    Experts explain that studies have shown coffee to have numerous potential health benefits, including improved cognitive function and reduced risk of some chronic conditions, including cancer ...

  8. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban (Xarelto) was the first approved FXa inhibitor to become commercially available in Europe and Canada in 2008. [1] The second one was apixaban (Eliquis), approved in Europe in 2011 [2] and in the United States in 2012. [3] The third one edoxaban (Lixiana, Savaysa) was approved in Japan in 2011 and in Europe and the US in 2015. [4]

  9. Boeing still needs a culture change to put safety above ... - AOL

    www.aol.com/boeing-still-needs-culture-change...

    A year after a panel blew out of a Boeing 737 Max during flight, the nation’s top aviation regulator says the company needs "a fundamental cultural shift” to put safety and quality above profits.

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