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The definition of "longest-living" used in this article considers only the observed or estimated length of an individual organism's natural lifespan – that is, the duration of time between its birth or conception, or the earliest emergence of its identity as an individual organism, and its death – and does not consider other conceivable ...
Extending telomeres can allow cells to divide more and increase the risk of uncontrolled cell growth and cancer development. [24] A study conducted by Johns Hopkins University challenged the idea that long telomeres prevent aging. Rather than protecting cells from aging, long telomeres help cells with age-related mutations last longer. [13]
In animal studies, maximum span is often taken to be the mean life span of the most long-lived 10% of a given cohort. By another definition, however, maximum life span corresponds to the age at which the oldest known member of a species or experimental group has died. Calculation of the maximum life span in the latter sense depends upon the ...
For sexually reproducing planaria: "the lifespan of individual planarian can be as long as 3 years, likely due to the ability of neoblasts to constantly replace aging cells". Whereas for asexually reproducing planaria: "individual animals in clonal lines of some planarian species replicating by fission have been maintained for over 15 years".
HeLa cells have been used to study expression of the papillomavirus E2 and apoptosis. [34] HeLa cells have also been used to study the ability of the canine distemper virus to induce apoptosis in cancer cell lines, [35] which could play an important role in developing treatments for tumor cells resistant to radiation and chemotherapy. [35]
The longest documented human lifespan is 122 years 164 days, the case of Jeanne Calment, who according to records was born in 1875 and died in 1997, whereas the maximum lifespan of a wildtype mouse, commonly used as a model in research on aging, is about three years. [10]
Telomerase was demonstrated in a 1998 publication in Science to be capable of extending cell lifespan, and now is well-recognized as capable of immortalizing human somatic cells. [41] Two studies on long-lived seabirds demonstrate that the role of telomeres is far from being understood
This is a list of maximum recorded animal lifespans in captivity.Only animals from the classes of the Chordata phylum are included. [1] On average, captive animals (especially mammals) live longer than wild animals.
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